Addressing Community Oncologists’ Questions About Novel Therapies for Non-Hodgkin Lymphoma — What Clinicians Want To Know

Faculty

Paolo F Caimi

MD

Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio

Professor of Medicine

Cleveland Clinic Cancer Center, Cleveland, Ohio

Associate BMT and CT Director for Cellular Therapy

Case Comprehensive Cancer Center, Cleveland, Ohio

Medical Director, Clinical Research Office

Faculty

Marc S Hoffmann

MD

University of Kansas Cancer Center, Kansas City, Kansas

Director, Lymphoma Program, Medical Director, Lean and Quality Improvement, Associate Professor, Division of Hematologic Malignancies and Cellular Therapeutics

Faculty

Brad S Kahl

MD

Washington University School of Medicine, St Louis, Missouri

Professor of Medicine

Siteman Cancer Center, St Louis, Missouri

Director, Lymphoma Program

Faculty

Sonali M Smith

MD

The University of Chicago, Chicago, Illinois

Elwood V Jensen Professor of Medicine, Chief, Section of Hematology/Oncology, Co-Leader, Cancer Service Line

Additional faculty to be announced.

Join us on Friday, December 11^th from 7:00 PM to 9:00 PM central time (8:00 PM to 10:00 PM eastern time).

MODULE 1: Clinical Utility of CD19-Directed Monoclonal Antibodies for Diffuse Large B-Cell Lymphoma (DLBCL) and Follicular Lymphoma (FL)

MODULE 2: Optimal Use of CD19-Directed Antibody-Drug Conjugates for Relapsed/Refractory DLBCL and FL

MODULE 3: Current and Future Role of Bruton Tyrosine Kinase Inhibition in the Management of NHL

MODULE 4: Role of Bcl-2 Inhibitors in the Management of Mantle Cell Lymphoma

Target Audience
This activity is intended for hematologists, medical oncologists, hematology-oncology fellows and other healthcare providers involved in the treatment of non-Hodgkin lymphoma.

Learning Objectives
At the conclusion of this activity, participants should be able to

• Understand published clinical research findings with CD19-targeted monoclonal antibodies in combination with immunomodulatory agents for diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL), and apply this information in patient-education discussions.
• Appraise the biological rationale for, available research findings with and current clinical role of CD19-targeted antibody-drug conjugates for patients with relapsed/refractory (R/R) DLBCL and FL.
• Evaluate available clinical trial findings with Bruton tyrosine kinase inhibitors for patients with mantle cell lymphoma (MCL), FL and DLBCL, and determine the utility of these agents in current and future clinical management.
• Assess the scientific basis for and available research findings with Bcl-2 inhibitors for patients with R/R MCL, and consider the current role of this novel therapeutic strategy.
• Review the mechanism of action and unique characteristics of cereblon E3 ligase modulators under development for FL and DLBCL, and appreciate available research findings with and ongoing studies evaluating the potential role of these novel agents.
• Recall new data with agents and strategies currently under investigation for various non-Hodgkin lymphoma subtypes, and discuss ongoing clinical trial opportunities with eligible patients.

CE Credit
CME credit information will be provided to each participant at the conclusion of the activity.

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Research To Practice is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement
Research To Practice designates this live activity for a maximum of 2 AMA PRA Category 1 Credits^TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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Unlabeled/Unapproved Uses Notice
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration. Research To Practice does not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. The opinions expressed are those of the presenters and are not to be construed as those of the provider or grantors.

Content Validation and Disclosures
Research To Practice (RTP) is committed to providing its participants with high-quality, unbiased and state-of-the-art education and adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of an accredited continuing education activity, including faculty, planners, reviewers and others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant financial relationships will have been mitigated prior to the commencement of this activity. In addition, all activity content is reviewed by RTP scientific staff and an external, independent physician reviewer for fair balance, scientific objectivity of studies referenced and patient care recommendations. Faculty disclosures to be announced.

FACULTY
To be announced.

MODERATOR
To be announced.

Research To Practice CME Planning Committee Members, Staff and Reviewers
Planners, scientific staff and independent reviewers for Research To Practice have no relevant financial relationships to disclose.

Supporters
This activity is supported by educational grants from ADC Therapeutics, AstraZeneca Pharmaceuticals LP, BeOne, and Bristol Myers Squibb.

Sheraton New Orleans Hotel
500 Canal Street
New Orleans, LA 70130
Hotel Phone: (504) 525-2500

Meeting Room
Napoleon Ballroom A/B — Third floor

Directions
The Sheraton New Orleans Hotel is located 0.9 miles (15-minute walk) from the New Orleans Ernest N Morial Convention Center, where the 2026 ASH Annual Meeting is taking place.

Program slides will be made available prior to the start of the session.

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