MM Working Group | Home


In April, RTP convened a Working Group of multiple myeloma (MM) clinical investigators, practicing hematologists/oncologists and oncology nurse practitioners (click here to see full faculty) to better elucidate current practice patterns in the management of this disease. The event featured a mix of didactic lectures, moderated, case-based discussions and extensive, real-time polling of the group intended to capture the preferred treatment strategies for a number of clinical scenarios.

The eight topic modules below — introduced sequentially via weekly emails over the next two months — provide access to the recorded discussions and conclusions that emerged from the event and are presented in the following formats (click here to view the the audio proceedings from this meeting):

  • Treatment Preference Matrix — Graphical summary of the investigators' preferred
    management approaches for four distinct clinical scenarios, including text-based
    commentary from select investigators.
  • Video Clip from MM Working Group — Short video segment featuring moderated panel discussion related to the topic module.
  • Video Presentations — Mini-lecture with slides by invited clinical investigators related to the topics discussed.
 
Workup, Risk Stratification and Pretransplant Induction Therapy
  • Nikhil C Munshi, MD — Workup and Risk Stratification
  • Sagar Lonial, MD — Risk Assessment in the Relapse Setting
  • Guido Tricot, MD, PhD — Induction Treatment for Younger Transplant-Ineligible Patients
 
Management of Side Effects and Toxicities of Systemic Treatment
  • Ivan Borrello, MD — Bortezomib-Associated Neuropathy
  • Jeffrey A Zonder, MD — Systemic Agents' Toxicities/Side Effects
 
Bone-Targeted Treatment
  • Melissa Alsina, MD — Bone-Targeted Treatment
  • Cristina Gasparetto, MD — Scheduling of Bone-Targeted Agents
  • David S Siegel, MD, PhD — Vertebroplasty and XRT
 
Special Cases
  • Video Clips from MM Working Group
    Faculty presentations and discussions of 7 patient cases:
    •  70 yo man with amyloidosis and macroglossia
    •  95 yo woman with CHF and MM
    •  80 yo woman with plasma cell leukemia
    •  47 yo woman with MGUS
    •  65 yo woman with MGUS
    •  47 yo woman with smoldering myeloma
    •  67 yo man with nonsecretory myeloma

  • Video Presentation
  • Carol Ann Huff, MD — Nutritional Support and Palliative Care
 
Method of Transplant and Post-Transplant Maintenance
  • Ravi Vij, MD — Post-Transplant Maintenance Therapy
  • William I Bensinger, MD — Delayed Transplantation
  • Edward A Stadtmauer, MD — Allo- and Tandem Transplantation
 
New Agents in Development
  • Rafael Fonseca, MD — New Agents in Development
  • Kenneth C Anderson, MD — Access to Trials in the Community Setting
 
Induction Treatment and Maintenance Therapy for Patients Not Eligible for Transplant
  • Antonio Palumbo, MD — Induction Therapy for Older Patients
  • A Keith Stewart, MBChB — Postinduction Maintenance
  • Morie A Gertz, MD — 60-80 yo with Adverse Cytogenetics
  • Jeffrey L Wolf, MD — 60-80 yo with Normal Cytogenetics
 
Management of Patients with Renal Failure
  • Ruben Niesvizky, MD — Induction Therapy for Older Patients with Comorbidities